Mark 3:20-21

Some of those whom you love with an agape love…will not extend that to you.

Hold fast to those revelations that God gives you.

Love God above all and love your neighbor as yourself.

Mark 3:20–21

20 Then the multitude came together again, so that they could not so much as eat bread. 21 But when His own people heard about this, they went out to lay hold of Him, for they said, “He is out of His mind.”

The Greek idiom used here for “his family” meaning “the ones from his side,” can refer to anyone who is closely related to a person, whether by blood or voluntary association. Jesus’ family might have wanted to preserve their reputation. The political ramifications of Jesus’ actions and teaching also could have caused His family to attempt to restrain Him, for fear of reprisal from Roman authorities or local Jewish leaders. Alternatively, they might have not have believed that Jesus was the Messiah and so attempted to silence Him to avoid being ostracized from the religious system (believing that it, too, would reject Him). 

Since Jesus has been at the center of a crowd almost continuously since His first teaching in Capernaum, it is unclear why His family reacts now. Faithlife Bible.

Opposition to Jesus came not only from His enemies. Jesus’ own people, no doubt close friends and perhaps even relatives, heard of His teaching and assumed that He was out of His mind. NKJ Bible.

Those who go on with zeal in the work of God, must expect hinderances, both from the hatred of enemies, and mistaken affections of friends, and need to guard against both. Matthew Henry Commentary.

Matthew 13:55 Is this not the carpenter’s son? Is not His mother called Mary? And His brothers James, Joses, Simon, and Judas?

Mark 6:3 Is this not the carpenter, the Son of Mary, and brother of James, Joses, Judas, and Simon? And are not His sisters here with us?” So they were offended at Him.

John 7:5 For even His brothers did not believe in Him.